Prescription Error Handling
Immediately notify the pharmacist if the prescription hasn't been dispensed. Mark the incorrect prescription in error in SystmOne, then re-issue the correct medication after double-checking patient identity.
A wrong medication, incorrect dosage, wrong route or frequency, or a prescription for the wrong patient was issued. This guide provides a structured response to minimize clinical risk, preserve the audit trail, and ensure patient safety.
Before You Start
- Access to the patient record with the incorrect prescription
- Pharmacy contact (phone or internal messaging)
- Your supervisor's contact (for high-risk medication errors)
- Familiarity with the Mark in Error workflow
Step-by-Step Instructions
Stop the Medication Process
Prevent the wrong medication from reaching the patient
- Immediately notify the pharmacist if the prescription has not yet been dispensed.
- If already dispensed, coordinate with pharmacy to retrieve or cancel the medication.
- If the patient has already taken the wrong medication, follow your clinic's adverse event protocol.
Mark the Error in SystmOne
Preserve the audit trail by formally marking the prescription in error
- Open the patient's record.
- Navigate to the Medications node in the Clinical Tree.
- Right-click on the incorrect prescription.
- Select Mark in Error.
- Choose the reason: "Wrong medication / dose / patient".
- Add a detailed explanation of what was wrong and why.
Re-Issue the Correct Prescription
Enter the accurate medication details
- Open a new prescription entry.
- Double-check patient identity: IC number and name.
- Enter the correct medication details:
- Correct drug name
- Correct dose
- Correct frequency
- Correct route
- Correct duration
- Verify before saving — review every field.
- Save and confirm the prescription is active.
Document and Communicate
Ensure all stakeholders are informed
- Add a note in the patient's journal explaining:
- What was prescribed in error
- What the correct prescription is
- Any actions taken (pharmacy notified, patient informed, etc.)
- Inform your supervisor if the error has clinical risk implications.
- Complete an incident report if required by clinic policy.
- Inform the patient if they were already aware of the original prescription.
Troubleshooting
Pharmacist already dispensed the wrong medication
Cause: The error was discovered after the patient received the medication.
Solution:
- Inform the patient immediately and advise them not to take the medication.
- Assess whether any clinical harm has occurred.
- Document the incident thoroughly in the patient journal.
- Notify your supervisor and follow the adverse event protocol.
- Complete a full incident report.
- Re-issue the correct prescription and ensure the patient understands the difference.
Cannot mark the prescription in error
Cause: The prescription may be locked, dispensed, or from another organization.
Solution:
- If already dispensed, coordinate with pharmacy to void the dispensation first.
- If the prescription is from another organization, use Request Mark in Error.
- Contact your clinic administrator or ICTSO if the system blocks the action.
- Document the error manually in the patient journal as an interim measure.
Patient was prescribed a drug they are allergic to
Cause: The allergy was overlooked during prescribing.
Solution:
- Stop the process immediately — this is a critical safety event.
- Notify pharmacy and the patient urgently.
- Mark the prescription in error with reason: "Prescribed contraindicated medication — patient allergy".
- Review the patient's allergy record and update it if incomplete.
- Inform your supervisor and complete an incident report.
- Re-prescribe a safe alternative after confirming no cross-reactivity.

